Tag results:
neural cells
Umbilical & Placental Cell News
Large-Scale Analysis of MicroRNA Expression in Motor Neuron-Like Cells Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells
[Scientific Reports] Human CB-MSCs were isolated and characterized using flow cytometry. Cell differentiation has been induced by combining retinoic acid and sonic hedgehog in a two-step protocol for 14 days.
Neural Cell News
SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection
[Frontiers in Molecular Neuroscience] Investigators tested the hypothesis that ZIKV-associated degeneration of neuronal processes was dependent on activation of Sterile alpha and armadillo motif-containing protein 1 (SARM1), an NADase that acted as a central executioner in a conserved axon degeneration pathway.
Cancer Stem Cell News
Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma
[Cancer Immunology Research] Scientists showed that circadian locomotor output cycles kaput (CLOCK) and its heterodimeric partner brain and muscle ARNT-like 1 in glioma stem cells drive immunosuppression in glioblastoma.
Cancer Stem Cell News
ISL1 Promotes Human Glioblastoma-Derived Stem Cells Self-Renewal by Activation of SHH/GLI1 Function
[Stem Cells and Development] Researchers established patient derived glioblastoma stem cells (GSCs), determined cancer stem cell marker expression, and immunostained GSCs to assess cell viability and apoptosis.
Cancer Stem Cell News
Phenotypic and Molecular States of IDH1 Mutation-Induced CD24-Positive Glioma Stem-Like Cells
[Neoplasia] The authors demonstrated that induction of a CD24-positive population is one mechanism by which IDH-mutant tumors acquired stem-like properties.
Cancer Stem Cell News
CHMP2A Regulates Tumor Sensitivity to Natural Killer Cell-Mediated Cytotoxicity
[Nature Communications] Scientists used a “two cell type” whole genome CRISPR-Cas9 screening system to discover key regulators of tumor sensitivity and resistance to natural killer cell-mediated cytotoxicity in human glioblastoma stem cells.