bronchial epithelial cells

[Journal of Clinical Investigation] Using androgen receptor (AR) deficient and Foxp3 fate-mapping mice, researchers determined that AR signaling increased Treg suppression during Alternaria extract challenge by stabilizing Foxp3+ Tregs and limiting the number of ST2+ ex-Tregs and IL-13+ Th2 and ex-Tregs.

[Inflammation] The authors evaluated the effects of the association between Cryptococcus neoformans and Dermatophagoides pteronyssinus in the modulation of airway inflammatory responses in an in vitro experimental model using human bronchial epithelial cells.

[International Journal of Biological Sciences] By applying untargeted global metabolomics approach, the authors showed that arsenic was highly capable of perturbing the intracellular metabolic programs of the human bronchial epithelial cells, some of which were prominent hallmarks of cancer cell metabolism.

[PLoS One] Researchers tested three classes of drugs commonly prescribed to treat asthma for their ability to promote barrier function using a cell culture model of virus-induced airway epithelial barrier disruption.

[Molecular Immunology] Researchers investigated whether Omarigliptin possessed a beneficial effect against LPS-induced injuries in human BEAS-2B bronchial epithelial cells.

[Toxicology in Vitro] Investigators have evaluated in vitro the binding and uptake by bronchial epithelial cells Calu-3 of 2 transuranic actinides, plutonium (Pu) and americium (Am), as the first steps of translocation across the pulmonary barrier.