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bronchial epithelial cells

Escherichia coli Infection Activates the Production of IFN-α and IFN-β via the JAK1/STAT1/2 Signaling Pathway in Lung Cells

[Amino Acids] Researchers studied whether E. coli infections could regulate interferon production and the underlying mechanisms. Two lung cell lines, a human bronchial epithelial cell line transformed with Ad12-SV40 2B and a human fetal lung fibroblast cell line, were used.

Down-Regulation of lncRNA MEG3 Promotes Chronic Low Dose Cadmium Exposure-Induced Cell Transformation and Cancer Stem Cell-Like Property

[Toxicology and Applied Pharmacology] The long non-coding RNA microarray analysis showed that the expression level of a tumor suppressive lncRNA maternally expressed 3 was significantly down-regulated in cadium-transformed cells, which was confirmed by further q-PCR analysis.

Serum-Derived Exosomes from House Dust Mite-Sensitized Guinea Pigs Contribute to Inflammation in BEAS-2B Cells via the TLR4-NF-κB Pathway

[Molecular Medicine Reports] The authors investigated whether serum exosomes played a pro‑inflammatory role in bronchial epithelial cells and explored the underlying molecular mechanisms.

Anti-inflammatory Actions of Aspirin-Triggered Resolvin D1 (AT-RvD1) in Bronchial Epithelial Cells Infected with Cryptococcus neoformans

[inflammopharmacology] The interaction of Cryptococcus neoformans with airway epithelial cells is crucial for the establishment of cryptococcosis. Scientists evaluated the effects of AT-RvD1 on human bronchial epithelial cells stimulated with C. neoformans.

Signaling Pathway Perturbation Analysis for Assessment of Biological Impact of Cigarette Smoke on Lung Cells

[Scientific Reports] Investigators reported the development of an algorithm based on quantitative assessment of transcriptomic profiles and signaling pathway perturbation analysis of human bronchial epithelial cells exposed to the toxic components present in cigarette smoke.

Single-Cell RNA Sequencing Identify SDCBP in ACE2-Positive Bronchial Epithelial Cells Negatively Correlates with COVID-19 Severity

[Journal of Cellular and Molecular Medicine] Since angiotensin-converting enzyme 2 (ACE2)-positive cells were hosts for COVID-19, researchers focussed on this cell type to explore the underlying mechanisms of COVID-19.

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