Escherichia coli Infection Activates the Production of IFN-α and IFN-β via the JAK1/STAT1/2 Signaling Pathway in Lung Cells

Researchers studied whether E. coli infections could regulate interferon production and the underlying mechanisms. Two lung cell lines, a human bronchial epithelial cell line transformed with Ad12-SV40 2B and a human fetal lung fibroblast cell line, were used.