cancer stem cells

[American Journal of Pathology] Downregulation of SET-domain containing 5 (SETD5) significantly decreased breast cancer stem-like cells properties and glycolysis in vitro and in vivo.

[Scientific Reports] Four types of human oral squamous carcinoma cell lines, non-radioresistant cell lines, and radioresistant cell lines, were used to measure the surviving fraction after single-dose irradiation, split-dose irradiation, and multi-fractionated irradiation.

[FASEB Journal] Scientists found estrogen receptor beta could increase the CSC population via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.

[Biochimie] The authors reviewed the recent progress of this signal transduction pathway in colorectal tumorigenesis.

[Cell Death & Disease] Scientists found that the low expression of RICH1 in breast cancer was associated with poor prognosis. Depletion of RICH1 promoted the stemness and disrupted the normal epithelial architecture of MCF10A cells.

[Cancer Gene Therapy] Scientists investigated the potential involvement of CLK4 in the metastasis and progression of mesenchymal-like (MES-) TNBC. In the MES-TNBC cell lines, the CLK4 expression was elevated.