RICH1 Inhibits Breast Cancer Stem Cell Traits through Activating Kinases Cascade of Hippo Signaling by Competing with Merlin for Binding to Amot-p80

Scientists found that the low expression of RICH1 in breast cancer was associated with poor prognosis. Depletion of RICH1 promoted the stemness and disrupted the normal epithelial architecture of MCF10A cells.