The authors summarize the latest advances regarding the particular involvement of point mutations of estrogen receptor alpha (ERα) in endocrine resistance. They also discuss the involvement of synonymous ERα mutations with respect to co-translational folding of the receptor and ribosome biogenesis in breast carcinogenesis.
[International Journal of Molecular Sciences]
Clusan, L., Le Goff, P., Flouriot, G., & Pakdel, F. (2021). A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses. International Journal of Molecular Sciences, 22(2), 756. https://doi.org/10.3390/ijms22020756 Cite
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