cancer stem cells

[Cell Death & Disease] Scientists delineate the key factors in pancreatic ductal adenocarcinoma derived extracellular vesicles that mediate different tumour processes.

[FEBS Journal] Scientists reported on the epidermal growth factor receptor (EGFR)-estrogen receptor beta (ERβ) functional relationship in connection to the aggressiveness and cancer stem cell-like characteristics of triple-negative breast cancer cells.

[Scientific Reports] Scientists clarified the significance of autophagy systems of CSCs under stress environments. Four gastric cancer cell line were used.

[Journal of Translational Medicine] The expression of miR-3065-3p in colorectal cancer and the association of miR-3065-3p expression with prognosis of patients with colorectal cancer were analyzed using TCGA dataset or clinical cases.

[Biomedicine & Pharmacotherapy] Researchers characterized a novel 12-kDa protein that named musarin, which was purified from Trametes versicolor mushroom extract and showed significant growth inhibition on multiple human colorectal cancer cell lines in vitro.

[Journal of Experimental & Clinical Cancer Research] The genetic manipulation of L1CAM in ovarian carcinoma (OC) cells provided gain and loss-of-function models that were then employed in cell biological assays as well as in vivo tumorigenesis experiments to assess the role of L1CAM in OC cell stemness and in ovarian OSC-driven tumor initiation.