cardiomyocytes

[Journal of Cellular Physiology] Researchers identified the potential roles of glycogen synthase kinase-3β, a critical regulator of cell proliferation and differentiation, in cardiac progenitor cell proliferation post-myocardial infarction.

[Molecular Medicine Reports] The authors explored the role and molecular mechanism of lncRNA small nucleolar RNA host gene 1 (SNHG1) in ischemic cardiomyocyte injury.

[Journal of Physiology] Using a comprehensive combination of genetically modified fish, electrophysiology, and gene expression analysis, scientists demonstrated that zebra fish cardiac myocytes and vascular smooth muscle expressed functional ATP-sensitive potassium channels channels of similar subunit composition, structure, and metabolic sensitivity to their mammalian counterparts.

[Cell Death & Disease] Researchers showed that nicotinamide played multiplex roles in mesoderm differentiation of human ESCs. Nicotinamide promoted cardiomyocyte fate from mesoderm progenitor cells, and suppressed the emergence of other cell types.

[Journal of Molecular and Cellular Cardiology] Investigators outline how to overcome hurdles in the production of functional cardiomyocytes from human iPSCs (hiPSCs-CMs) to realize the transplantation of hiPSC-CMs in patients with heart failure and introduce cutting-edge findings and perspectives for future regenerative therapy.

[Cardiovascular Toxicology] Researchers investigated the protective effects of Metoprolol against arginine vasopressin-induced cellular senescence in cultured cardiomyocytes.