Production of Functional Cardiomyocytes and Cardiac Tissue from Human Induced Pluripotent Stem Cells for Regenerative Therapy

Investigators outline how to overcome hurdles in the production of functional cardiomyocytes from human iPSCs (hiPSCs-CMs) to realize the transplantation of hiPSC-CMs in patients with heart failure and introduce cutting-edge findings and perspectives for future regenerative therapy.