High glucose induced cardiomyocyte hypertrophy, accompanied by abnormal mitochondrial morphology and function, and increased Orai1-mediated Ca2+ influx.
[Cell Death & Disease]
Wu, Q.-R., Zheng, D.-L., Liu, P.-M., Yang, H., Li, L.-A., Kuang, S.-J., Lai, Y.-Y., Rao, F., Xue, Y.-M., Lin, J.-J., Liu, S.-X., Chen, C.-B., & Deng, C.-Y. (2021). High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy. Cell Death & Disease, 12(2), 1–15. https://doi.org/10.1038/s41419-021-03502-4 Cite
0