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cell proliferation

Involvement of TMEM16A/ANO1 Upregulation in the Oncogenesis of Colorectal Cancer

[Biochimica Et Biophysica Acta-Molecular Cell Research] Scientists showed that ANO1 channel protein was upregulated in human colorectal cancer tissue samples and its upregulation was correlated with the TNM staging, histological type, pathological differentiation and poor prognosis.

Boric Acid Suppresses Cell Proliferation by TNF Signaling Pathway Mediated Apoptosis in SW-480 Human Colon Cancer Line

[Journal of Trace Elements in Medicine and Biology] Scientists investigated whether boric acid could be a new candidate molecule that could be used in the treatment of colon cancer.

Knockdown of Long Non-Coding RNA DDX11-AS1 Inhibits the Proliferation, Migration and Paclitaxel Resistance of Breast Cancer Cells by Upregulating MicroRNA-497 Expression

[Molecular Medicine Reports] Reverse transcription‑quantitative PCR was used to detect the expression levels of DDX11 antisense RNA 1 (DDX11-AS1) and microRNA‑497 in MCF‑7 and MDA‑MB‑231 cells.

Small Molecule LATS Kinase Inhibitors Block the Hippo Signaling Pathway and Promote Cell Growth under 3D Culture Conditions

[Journal of Biological Chemistry] The authors found that a molecule designated GA-017 increased the number and size of spheroids of various cell-types in both scaffold-based and scaffold-independent cultures.

Lucidone Inhibits Autophagy and MDR1 via HMGB1/RAGE/PI3K/Akt Signaling Pathway in Pancreatic Cancer Cells

[Phytotherapy Research] Investigators explored the function of lucidone in tumor cytotoxicity and chemosensitivity through the suppression of receptor for advanced glycation end products-initiated signaling in pancreatic ductal adenocarcinoma cells.

MiR-29b-3p Inhibits the Inflammation Injury in Human Umbilical Vein Endothelial Cells by Regulating SEC23A

[Biochemical Genetics] The authors investigated the effects of miR-29b-3p on the inflammation injury of HUVECs induced by lipopolysaccharide and explored the underlying mechanisms.

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