Tag results:
cell proliferation
Pulmonary Cell News
E2F1-Induced lncRNA, EMSLR Regulates lncRNA LncPRESS1
[Scientific Reports] The authors carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which was induced both in lung adenocarcinoma and lung squamous cell carcinoma.
Pulmonary Cell News
Regulation of MHC Class I Expression in Lung Epithelial Cells during Inflammation
[Journal of Immunology] The authors reported that inhalation of the TLR4 ligand LPS upregulated cell surface MHC class I by ∼25-fold on the three subtypes of mouse lung epithelial cells.
Prostate Cell News
TRPC3 Shapes the ER-Mitochondria Ca2+ Transfer Characterizing Tumour-Promoting Senescence
[Nature Communications] Researchers reported the mechanism altering mitochondrial function and OXPHOS in stress-induced senescent fibroblasts.
ESC & iPSC News
The Significance of ErbB2/3 in the Conversion of Induced Pluripotent Stem Cells into Cancer Stem Cells
[Scientific Reports] Scientists analyzed the transcriptome of cancer stem cells, which were converted from iPSCs with conditioned medium from pancreatic ductal adenocarcinoma cells.
Hepatic Cell News
Cell Adhesion Molecule KIRREL1 Is a Feedback Regulator of Hippo Signaling Recruiting SAV1 to Cell-Cell Contact Sites
[Nature Communications] The authors suggested that KIRREL1 functioned as a feedback regulator of the mammalian Hippo pathway through sensing cell-cell interaction and recruiting SAV1 to cell-cell contact sites.
Immune Regulation News
LIGHT Enhanced Bispecific Antibody Armed T Cells to Treat Immunotherapy Resistant Colon Cancer
[Oncogene] Scientists demonstrate that activated T cells armed with anti-CD3 x anti-EGFR bispecific antibody increases tumor infiltrating lymphocytes and mediate anti-tumor cytotoxicity while decreasing tumor cell viability.