cell proliferation

[Theranostics] Scientists demonstrated that transforming growth factor-β-activated kinase 1 (TAK1) played an important role in the pathogenesis of corneal neovascularization.

[Cell Death & Disease] This research was designed to explore the mechanism underlying the OLR1/c-MYC/SULT2B1 axis in the regulation of glycolytic metabolism, to affect colon cancer cell proliferation and chemoresistance.

[Nature Metabolism] Researchers identified the myokine/cytokine Meteorin-like (Metrnl) as a critical regulator of muscle regeneration.

[Cell Death & Disease] The authors identified a novel long non-coding RNA KDM4A-AS1, which was aberrantly overexpressed in hepatocellular carcinoma (HCC) tissues, associated with unfavorable clinical features and poor prognosis of patients. KDM4A-AS1 promoted HCC cell proliferation, migration, and invasion in vitro and contributed to HCC growth and lung metastasis in vivo.

[Scientific Reports] Investigators explored the regulatory mechanism of circFOXM1 in hepatocellular carcinoma (HCC) proliferation and metastasis. RNA polymerase inhibitor actinomycin D and RNase R exonuclease were used to identify circFOXM1 in HCC cells.

[Cell Death Discovery] Scientists investigated the function and mechanism of LINC00667 in hepatocellular carcinoma progression. The effects of LINC00667 silencing in cell proliferation, cell migration, and cell invasion, and androgen receptor expression were determined with loss-of-function phenotypic analysis in Huh-7 and HCCLM3 cells.