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cell proliferation

Autonomic Control of Pancreatic Beta Cells: What Is Known on the Regulation of Insulin Secretion and Beta-Cell Proliferation in Rodents and Humans

[Peptides] Investigators describe mechanisms involved in insulin secretion as well as metabolic and mitogenic actions on its target tissues.

Taurine Stimulates Protein Synthesis and Proliferation of C2C12 Myoblast Cells through the PI3K-ARID4B-mTOR Pathway

[British Journal of Nutrition] Researchers investigated the role and underlying molecular mechanism of Tau on protein synthesis and proliferation of C2C12 myoblast cells.

Nuclear Paraspeckle Assembly Transcript 1 Enhances Hydrogen Peroxide-Induced Human Vascular Smooth Muscle Cell Injury by Regulating miR-30d-5p/a Disintegrin and Metalloprotease 10

[Circulation Journal] The expression of nuclear paraspeckle assembly transcript 1, miR-30d-5p and A disintegrin and metalloprotease 10 was measured by qRT-PCR and western blot. Functional experiments were conducted by using a CCK-8 assay, EDU assay, flow cytometry, western blot, ELISA, and commercial kits.

Polygonatum sibiricum Polysaccharides (PSP) Improve the Palmitic Acid (PA)-Induced Inhibition of Survival, Inflammation, and Glucose Uptake in Skeletal Muscle Cells

[Bioengineered] The underlying molecular mechanisms of PSP in improving insulin resistance (IR) in skeletal muscle remain unclear. PA induced an IR model in L6 myotubes. After treatment, cell proliferation was measured using the CCK8.

A Tumor-Derived Type III Collagen-Rich ECM Niche Regulates Tumor Cell Dormancy

[Nature Cancer] Investigators studied how disseminated tumor cells sensed and remodeled the ECM to sustain dormancy.

Genome-Wide Fitness Gene Identification Reveals Roquin as a Potent Suppressor of CD8 T Cell Expansion and Anti-Tumor Immunity

[Cell Reports] Investigators performed in vivo and in vitro CRISPR screens to systematically identify genes influencing CD8 T cell expansion.

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