cell proliferation

[Oncogene] The authors found that RGMA was downregulated in breast cancer (BC) tissues compared with non-tumorous breast tissues, particularly in metastatic BC samples, and that patients with low RGMA expression manifested a poorer prognosis.

[Cell Death Discovery] Researchers discovered that TRAF7 was overexpressed in hepatocellular carcinoma tumor tissues and the increased TRAF7 expression was closely associated with tumor size, histologic grade, TNM stage and poor prognostication.

[Cell Death & Disease] Researchers investigated the mechanism by which nucleolar and spindle-associated protein 1 enhanced chemoresistance via DNA damage repair signaling by stabilizing RAD51 in chronic lymphocytic leukemia cells.

[Environmental Toxicology] Dysregulated miRNAs have been promulgated as oncogenes or tumor-suppressive genes participating in the initiation and progression of colorectal cancer (CRC). Scientists reported that miR-346 was highly expressed in CRC patients.

[Journal of Biomedical Science] The role of Receptor tyrosine kinase-like orphan receptor 2 (ROR2) in tumor growth was assessed in xenotransplantation experiments followed by immunohistochemistry analysis of the tumors.

[Metabolic Brain Disease] Investigators explored the potential role and mechanism of circ_0057583 in brain microvascular endothelial cell injury. Human brain microvascular endothelial cells were exposed to different doses of lipopolysaccharide to induce cell damage.