cell proliferation

[Communications Biology] Investigators reported the development of a high-throughput RNAi screening approach to identify upstream pathways that regulated adult human β cell quiescence and demonstrated in a screen of the GPCRome that silencing G-protein coupled receptor 3 (GPR3) led to human pancreatic β cell proliferation.

[Cell Death & Disease] Investigators demonstrated that miR-4293 expression was markedly enhanced in lung carcinoma tissue and cells and miR-4293 promoted tumor cell proliferation and metastasis but suppressed apoptosis.

[Cell Biology International] Cardiac function, myocardial infarction area, apoptosis, and angiogenesis were all evaluated in a CHF rat model following treatment with human umbilical cord MSC-derived exosomes.

[Oncology Reports] Investigators investigated the inhibitory effect of miR‑367‑3p on the proliferation, invasion, and metastasis of prostate cancer cells.

[Nutrition and Cancer] The authors evaluated the effects of sterculic oil from Sterculia apetala seeds on proliferation, cell cycle and apoptosis in prostate cancer cells.

[Journal of Experimental Medicine] Researchers showed that mice deficient in the prostaglandin D2 receptor CRTH2 and mice with CRTH2 deficiency only in nonhematopoietic cells exhibited enhanced worm clearance and intestinal goblet cell hyperplasia following infection with the helminth Nippostrongylus brasiliensis.