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chondrocytes

3D Bioprinted Silk Fibroin Hydrogels for Tissue Engineering

[Nature Protocols] Investigators developed a methacrylated photocurable silk fibroin bioink for digital light processing 3D bioprinting to generate structures with high mechanical stability and biocompatibility for tissue engineering applications.

Dual Crosslinked Pullulan-Gelatin Cryogel Scaffold for Chondrocyte-Mediated Cartilage Repair: Synthesis, Characterization and In Vitro Evaluation

[Biomaterials Science] Chondrocytes seeded within a a dual crosslinked pullulan-gelatin cryogel scaffold and cultured for 21 days in vitro demonstrated enhanced cell proliferation, enhanced production of cartilage-specific ECM and up-regulated sulfated glycosaminoglycan without altering the articular chondrocyte phenotype.

Biomimetic Scaffolds Modulate the Post-Traumatic Inflammatory Response in Articular Cartilage Contributing to Enhanced Neo-Formation of Cartilaginous Tissue In Vivo

[Advanced Healthcare Materials] A chondrogenic collagen-chondroitin sulfate scaffold was tested in an orthotopic lapine in vivo model to understand the beneficial effects of the immunomodulatory biomaterial on full chondral defect.

Roles of Mechanosensitive Channel Piezo1/2 Proteins in Skeleton and Other Tissues

[Bone Research] The authors emphasize the diverse functions of Piezo1 and Piezo2 and related signaling pathways in osteoblast lineage cells and chondrocytes, and summarize key findings about PIEZO gene mutations in human diseases.

DNA Barcode to Trace the Development and Differentiation of Cord Blood Stem Cells

[Molecular Medicine Reports] The latest research findings on the development and differentiation, culture techniques and labeling and tracing of umbilical cord blood stem cells are reviewed.

Safety and Efficacy of Human Juvenile Chondrocyte-Derived Cell Sheets for Osteochondral Defect Treatment

[NPJ Regenerative Medicine] Investigators demonstrated preclinical safety and efficacy of scaffold-free, human juvenile cartilage-derived-chondrocyte sheets produced from routine surgical discards using thermo-responsive cultureware.

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