clinical trial

[Stem Cells International] Investigators manufactured neprilysin gene-enhanced human umbilical cord-derived MSCs and intravenously transplanted them in Aβ1-42-injected Alzheimer’s disease animal models.

[Stanford Health] Sanford Health announced a stem cell trial expanding the use of adult-adipose derived stem cells in the use of osteoarthritis across five joints. The clinical trial, called the ENDURE trial, is the first of its kind study.

[HiberCell, Inc.] HiberCell announced a clinical trial collaboration with Merck. This metastatic breast cancer clinical trial evaluates KEYTRUDA®, Merck’s anti-PD-1 therapy, in combination with HiberCell’s odetiglucan, a Dectin-1, pattern recognition receptor agonist.

[BeiGene] BeiGene announced entry into a license and collaboration agreement granting BeiGene worldwide research, development and manufacturing rights and exclusive commercialization rights outside of China to LBL-007, a novel investigational antibody targeting the LAG-3 pathway.

[Mustang Bio, Inc.] Mustang Bio, Inc. announced updated data from the ongoing Phase I/II clinical trial of MB-106, a CD20-targeted, autologous CAR T cell therapy for patients with relapsed or refractory B cell non-Hodgkin lymphomas and chronic lymphocytic leukemia.

[Nature News] Molnupiravir, one of two antiviral pills that have caused excitement in the past few months because preliminary clinical-trial results showed that they can significantly reduce hospitalizations and deaths from COVID-19, has yet to receive an emergency use authorization from the US FDA.