colorectal cancer

[Kaohsiung Journal of Medical Sciences] Researchers showed that the upregulation of thrombospondin 2 (THBS2) in colorectal cancer (CRC) tissues and CRC cell lines and high expression of THBS2 was correlated with poor overall survival.

[Nature Communications] Scientists reported that pumolio homolog 1 (Pum1) and Pum2 displayed increased expression in human colorectal cancer.

[Cell Death Discovery] In functional in vitro experiments, researchers observed that calmodulin-binding transcription activator 1 (Camta1) overexpression significantly decreased the proliferation and invasion capacity of SW620 and SW480 cells.

[Journal of Biomedical Science] 4’,5,7-trihydroxyisoflavone probe was a new chemical probe inhibitor of signal transducer and activator of transcription 1 (STAT1) that reduced stemness and angiogenesis in colorectal cancer.

[Stem Cell Research & Therapy] Researchers constructed a stemness index for single-cell samples (StemSC) based on relative expression orderings of gene pairs.

[Clinical Cancer Research] Tumor and blood samples were analyzed by flow cytometry, immunohistochemistry, transcriptome and cytokine profiling. Cabozantinib-related effects were validated in a colorectal cancer PDX model.