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Cord Blood News

Engraftment Kinetics after Transplantation of Double Unit Cord Blood Grafts Combined with Haplo-Identical CD34+ Cells without Antithymocyte Globulin

[Leukemia] Scientists investigated adding haplo-identical CD34+ cells to double unit cord blood (CB) grafts to facilitate early haplo-identical donor-derived neutrophil recovery prior to CB engraftment.

Chi-Med Announces Fruquintinib Granted US FDA Fast Track Designation for Metastatic Colorectal Cancer

[Hutchison China MediTech Limited ] Hutchison China MediTech Limited announced that the FDA has granted Fast Track Designation for the development of fruquintinib, for the treatment of patients with metastatic colorectal cancer who have been previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and, if RAS wild-type, an anti-epidermal growth factor receptor therapy.

NMPA Accepts Bio-Thera Solutions’ Biologics License Application (BLA) for BAT1706, A Proposed Biosimilar to Avastin®

[Bio-Thera Solutions (Business Wire, Inc.)] Bio-Thera Solutions announced that the China National Medical Products Administration (NMPA) has accepted the Biologics License Application for BAT1706, a proposed biosimilar to Avastin®.

Proteomic Profiling of Striatal Tissue of a Rat Model of Parkinson’s Disease after Implantation of Collagen-Encapsulated Human Umbilical Cord Mesenchymal Stem Cells

[Journal of Tissue Engineering and Regenerative Medicine] Human umbilical cord-MSCs were encapsulated into collagen hydrogels and implanted into the striatum of hemi‐parkinsonian male Sprague Dawley rats. One or 14 days after implantation, the area of interest was dissected using a cryostat.

Enhanced Collection of Phenotypic and Engrafting Human Cord Blood Hematopoietic Stem Cells at 4°C

[Stem Cells] Researchers demonstrated that collecting and processing of human cord blood at 4°C within minutes of the baby's birth results in significantly enhanced numbers of rigorously defined phenotypic hematopoietic stem cell and self‐renewing NSG immune‐deficient mouse engrafting and SCID‐repopulating cells.

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