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COVID-19

Intranasal Administration of BReC-CoV-2 COVID-19 Vaccine Protects K18-hACE2 Mice against Lethal SARS-CoV-2 Challenge

[NPJ Vaccines] Scientists developed a prototype two-dose vaccine by combining the Receptor Binding Domain antigen, via conjugation to Diphtheria toxoid.

Mild SARS-CoV-2 Infection in Rhesus Macaques Is Associated with Viral Control Prior to Antigen-Specific T Cell Responses in Tissues

[Science Immunology] The authors used rhesus macaques to model protective primary immune responses in tissues during mild COVID-19.

Aeterna Zentaris Announces Expansion of Research Program with Julius-Maximilians-University Wuerzburg Aiming to Accelerate Development of Vaccine Programs

[Aeterna Zentaris, Inc.] Aeterna Zentaris, Inc. announced it has expanded the scope of its existing research program with the Julius-Maximilians-University Wuerzburg, on the development of COVID-19 and Chlamydia trachomatis vaccines.

Safety and Efficacy Study of Allogeneic Human Menstrual Blood Stromal Cells Secretome to Treat Severe COVID-19 Patients: Clinical Trial Phase I & II

[Stem Cell Research & Therapy] A prospective randomized double-blind placebo-controlled clinical trial assessed the safety and efficacy of secretome derived from allogeneic menstrual blood stromal cells as a treatment in patients with severe COVID-19.

KIR+CD8+ T Cells Suppress Pathogenic T Cells and Are Active in Autoimmune Diseases and COVID-19

[Science] CD8+ T expressing inhibitory killer cell immunoglobulin-like receptors cells efficiently eliminated pathogenic gliadin-specific CD4+ T cells from celiac disease patients’ leukocytes in vitro.

Immunity to SARS-CoV-2: What Do We Know and Should We Be Testing for It?

[Journal of Clinical Microbiology] Investigators discuss what Correlates of Protections are, review the current understanding of infection-induced, vaccine-elicited and hybrid immunity to COVID-19 and summarize the current and potential future utility of SARS-CoV-2 serologic testing.

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