COVID-19

[International Journal of Biological Sciences] Scientists summarize the physiological and pathological damage of SARS-CoV-2 to these systems and its molecular mechanisms followed by clinical manifestation.

[Cellular & Molecular Immunology] Investigators reported the immunogenicity and protection induced in rhesus macaques by intramuscular injections of a virus-like particle bearing a SARS-CoV-2 spike protein vaccine candidate formulated with or without Adjuvant System 03 or cytidine-phospho-guanosine 1018.

[Pfizer, Inc.] Pfizer, Inc. and BioNTech SE announced a new research, development and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles.

[NPJ Vaccines] Utilizing multiple influenza antigens, scientists demonstrated the suitability of the mRNA therapeutic platform for such applications.

[Ageing Research Reviews] Driven by this research, scientists provide a comprehensive and up-to-date overview of the various rebalancing capabilities of zinc in the unbalanced immune system of the elderly.

[Signal Transduction and Targeted Therapy] Scientists showed that SARS-CoV-2-triggered mast cells degranulation initiated alveolar epithelial inflammation and lung injury.