dendritic cells

[Circulation] Investigators utilized mouse models of reperfused myocardial infarction, angiotensin II and phenylephrine infusion, and diphtheria toxin cardiomyocyte ablation to investigate C-C chemokine ligand 17.

[Haematologica] Dendritic cells were either generated from monocytes or isolated directly from blood of healthy donors or graft-versus-host disease patients and co-cultured in a mixed lymphocyte reaction with T cells obtained from healthy donors or transplantation bags.

[Journal of Leukocyte Biology] Researchers showed that myeloid cells from cord blood could be activated to express T cell costimulatory markers, and also to produced Th1 promoting cytokines.

[Akeso, Inc. (PR Newswire, Inc.)] Akeso, Inc. announced that Ligufalimab and Ivonescimab have obtained approval from the Center for Drug Evaluation of the National Medical Products Administration of the People's Republic of China to initiate a Phase II clinical trial with chemotherapy as first-line therapy for unresectable locally advanced or metastatic triple negative breast cancer.

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

[Cellular and Molecular Life Sciences] Scientists established cultures of murine bone marrow-derived dendritic cells that lacked sialic acid expression using a sialic acid-blocking mimetic Ac53FaxNeu5Ac.