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dermal cells

FGFR2 Maintains Cancer Cell Differentiation via AKT Signaling in Esophageal Squamous Cell Carcinoma

[Cancer Biology & Therapy] Scientists showed that fibroblast growth factor receptor 2 (FGFR2), particularly the IIIb isoform, was highly expressed in non-CSCs.

Collagen/Glycosaminoglycan-Based Matrices For Controlling Skin Cell Responses

[Biological Chemistry] The authors address recent findings for enhanced epidermal-dermal regenerative processes on collagen/glycosaminoglyca(GAG)n-based matrices containing sulfated GAG in simple and complex in vitro models.

AP-2alpha-Mediated Activation of E2F and EZH2 Drives Melanoma Metastasis

[Cancer Research] Researchers demonstrated that AP-2alpha facilitated melanoma metastasis through transcriptional activation of genes within the E2F pathway including EZH2.

Dominant Effect of Gap Junction Communication in Wound-Induced Calcium-Wave, NFAT Activation and Wound Closure in Keratinocytes

[Journal of Cellular Physiology] Real-time cell migration analysis, measuring wound closure rates over 24 hours, revealed that 18αGA essentially blocked wound closure whereas hexokinase and GSK-7975A showed relatively minimal effects.

Dermal Mesenchymal Stem Cells from Psoriatic Lesions Stimulate HaCaT Cell Proliferation, Differentiation, and Migration via Activating the PI3K/AKT Signaling Pathway

[Dermatology] Scientists studied the effects of psoriatic dermal mesenchymal stem cells on the proliferation, differentiation, and migration of keratinocytes and the underlying mechanisms.

Circ_PRKDC Knockdown Promotes Skin Wound Healing by Enhancing Keratinocyte Migration via miR-31/FBN1 Axis

[Journal of Molecular Histology] The migration ability and the changes of matrix metallopeptidase 9 (MMP-9) and MMP2 levels were determined using wound healing, transwell and Western blot assays.

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