dermal cells

[Oncology Letters] The authors demonstrated that chemical manipulation of esophageal keratinocyte differentiation in mouse normal esophageal epithelial organoids implicated the involvement of the mouse homologue of ZNF750, Zfp750, in keratinocyte differentiation in premalignant cells.

[Ebiomedicine] Scientists found increased average methylation in mouse cutaneous squamous cell carcinomas (cSCC) as well as in stem-cell like, but not keratinocyte-like, human cSCC.

[Cell Death & Disease] Researchers found that the expression of NEDD4-binding protein 1 (N4BP1) in skin was highest among all 54 tested tissues, and its expression was further upregulated in psoriatic skin.

[Scientific Reports] Scientists aimed to evaluate the protective effect of a methanol extract of Sargassum horneri (SHM), which contains 6-hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one (HTT) and apo-9′-fucoxanthinone, against ultraviolet B (UVB)-induced cellular damage in human keratinocytes and its underlying mechanism.

[Scientific Reports] Researchers detected a significantly reduced A375 cell viability, an increase in alanine, inositol, nucleotides, and other metabolites that together define apoptosis.

[Immunity] Scientists demonstrated that inhibition of protein synthesis during viral infection is sensed as a virulence strategy and initiates pyroptosis in human keratinocytes.