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dermal cells

New Emerging Treatment Options for Advanced Basal Cell Carcinoma and Squamous Cell Carcinoma

[Advances in Therapy] The authors analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.

The Application of Mesenchymal Stromal Cells (MSCs) and Their Derivative Exosome in Skin Wound Healing: A Comprehensive Review

[Stem Cell Research & Therapy] Scientists overview recent in vivo reports rendering the therapeutic benefits of the MSCs-based therapies to ease skin wound healing, and so improving quality of life among patients suffering from such conditions.

Trehangelins Ameliorate Inflammation-Induced Skin Senescence by Suppressing the Epidermal YAP-CCN1 Axis

[Scientific Reports] Researchers described a possible mechanism involved in skin aging focusing on the effect of Trehangelins on epidermal cellular communication metwork factor 1 (CCN1).

Discrimination of Hand-Foot Skin Reaction Caused by Tyrosine Kinase Inhibitors Based on Direct Keratinocyte Toxicity and Vascular Endothelial Growth Factor Receptor-2 Inhibition

[Biochemical Pharmacology] The authors explained the incidence of hand-foot skin reaction in patients treated with tyrosine kinase inhibitors by focusing on keratinocyte toxicity and inhibition of vascular endothelial growth factor receptor, which played an essential role in angiogenesis.

Reduced Expression of Collagen 17A1 in Naturally Aged, Photoaged, and UV-Irradiated Human Skin In Vivo: Potential Links to Epidermal Aging

[Journal of Cell Communication and Signaling] Researchers found that matrix metalloproteinases were responsible for ultraviolet (UV)-mediated Collagen 17A degradation in both in vitro keratinocytes and in vivo mouse skin.

TSLP Impairs Epidermal Barrier Integrity by Stimulating the Formation of Nuclear IL-33/Phosphorylated STAT3 Complex in Human Keratinocytes

[Journal of Investigative Dermatology] Researchers stimulated post-confluent human keratinocytes and living skin equivalent with TSLP to investigate the role of nuclear IL-33 in TSLP-induced epidermal barrier defects.

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