Tag results:
endothelial cells
Extracellular Matrix News
Oxidative Pentose Phosphate Pathway Controls Vascular Mural Cell Coverage by Regulating Extracellular Matrix Composition
[Nature Metabolism] The authors demonstrated that endothelial cell metabolism regulated blood vessel maturation by controlling vascular matrix composition and vascular mural cell recruitment.
Endothelial Cell News
Extracellular Vimentin Is an Attachment Factor That Facilitates SARS-CoV-2 Entry into Human Endothelial Cells
[Proceedings of the National Academy of Sciences of the United States of America] The authors described the identification of vimentin, an intermediate filament protein widely expressed in cells of mesenchymal origin, as an important attachment factor for SARS-CoV-2 on human endothelial cells.
Endothelial Cell News
Heterogeneity in Endothelial Cells and Widespread Venous Arterialization during Early Vascular Development in Mammals
[Cell Research] Scientists constructed the single-cell transcriptomic landscape of vascular endothelial cells during the time window for the occurrence of key vasculogenic and angiogenic events in both mouse and human embryos.
Neural Cell News
Extracellular Vesicles from Adipose-Derived Stem Cells Promote Microglia M2 Polarization and Neurological Recovery in a Mouse Model of Transient Middle Cerebral Artery Occlusion
[Current Stem Cell Research & Therapy] The authors explored the contribution of miRNAs in adipose-derived stem cell-extracellular vesicles to the treatment of cerebral ischemia.
Pulmonary Cell News
Characterization of the COPD Alveolar Niche Using Single-Cell RNA Sequencing
[Nature Communications] The authors analyzed single-cell RNA sequencing profiles of explanted lung tissue from subjects with advanced COPD or control lungs and identified a subpopulation of alveolar epithelial type II cells with transcriptional evidence for aberrant cellular metabolism and reduced cellular stress tolerance in COPD.
Muscle Cell News
Overexpression of the SARS-CoV-2 Receptor Angiotensin Converting Enzyme 2 in Cardiomyocytes of Failing Hearts
[Scientific Reports] Scientists examined the expression of ACE2 in normal hearts and hearts from patients with terminal heart failure.