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endothelial cells

Exosomal miR-1260b Derived from Non-small Cell Lung Cancer Promotes Tumor Metastasis through the Inhibition of HIPK2

[Cell Death & Disease] Researchers investigated the role of exosomal miR-1260b derived from non-small cell lung cancer in tumor progression.

Plasma Extracellular Vesicle Delivery of miR-210-3p by Targeting ATG7 to Promote Sepsis-Induced Acute Lung Injury by Regulating Autophagy and Activating Inflammation

[Experimental & Molecular Medicine] Scientists elucidated the role of plasma extracellular vesicles in delivering miR-210-3p in sepsis-induced acute lung injury.

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Probable Triggers of Radiation-Induced Heart Disease

[Stem Cell Research & Therapy] Scientists examined the hypothesis that the altered secretion of extracellular vesicles from MSCs was the trigger of radiation-induced heart disease.

Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis

[Nature Communications] Researchers explored the mechanistic role of super-enhancers linking cytokine TNFα with chemokine amplification in alcoholic hepatitis.

PDGF-BB/SA/Dex Injectable Hydrogels Accelerate BMSC-Mediated Functional Full Thickness Skin Wound Repair by Promoting Angiogenesis

[Journal of Materials Chemistry B] Scientists showed that the Platelet derived growth factor-BB (PDGF-BB)/sodium alginate (SA)/dextran (Dex) hydrogels could sustainably release PDGF-BB with excellent biocompatibility in vitro and in vivo.

Bio-Engineering a Prevascularized Human Tri-layered Skin Substitute Containing a Hypodermis

[Acta Biomaterialia] Severe injuries to skin including hypodermis require full-thickness skin replacement. Researchers bio-engineered a tri-layered human skin substitute containing the epidermis, dermis, and hypodermis.

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