endothelial cells

[Signal Transduction and Targeted Therapy] Investigators showed that externalized phosphatidylserine (PS) was observed on the surface of colonic capillaries. Annexin A5 with high affinity for PS had a good targeting to the colon and effectively alleviated experimental colitis.

[Molecular Medicine Reports] The authors investigated the role of high shear stress (HSS) in atherosclerotic plaque formation. In vitro modeling used human umbilical vein endothelial cells and vascular smooth muscle cells exposed to HSS using a parallel‑plate flow system.

[Nature Communications] Scientists generated p32 chimeric antigen receptors (CAR) T cells and found them to recognize and specifically eliminate p32 expressing glioma cells and tumor derived endothelial cells in vitro and to control tumor growth in orthotopic syngeneic and xenograft mouse models.

[Journal of Cellular Physiology] Scientists discuss the evidence for nitric oxide as a critical player of placental development and function, with a special focus on endothelial nitric oxide synthase vascular effects.

[Biochemical and Biophysical Research Communications] Scientists utilized a β3-endonexin mutant carrying a defective nuclear localization sequence to disrupt its nuclear localization and evaluated its ability to promote HUVEC proliferation and formation of tube-like vascular structures.

[Current Stem Cell Research & Therapy] Investigators investigated whether human endometrium-derived stem cells could be used for cardiac repair after ischemic injury and their possible underlying mechanisms.