endothelial progenitor cells

[Scientific Reports] Investigators proposed that replacing donor endothelial cells alone, while keeping the rest of the organ viable and functional, is more technically feasible, and may offer a significant shortcut in the efforts to engineer transplantable organs.

[PLOS ONE] Scientists characterized venous malformation endothelial and mural cell expression by performing a comprehensive expression analysis of venous malformation vasculature.

[Haematologica] Researchers used induced pluripotent stem cell technology and established a 3D, organoid-like differentiation system maintaining the structural cellular integrity to evaluate the effect of cytokines on embryonic hematopoietic development.

[Stem Cell Research] Peripheral blood mononuclear cells were isolated from age-matched control subjectsand end-stage renal disease patients, followed by culture in either conventional endothelial progenitor cell culture for one month or in quality and quantity culture for seven days, respectively.

[American Journal of Respiratory and Critical Care Medicine] Single cell RNA sequencing of neonatal human and mouse lung was used to identify the heterogeneity of pulmonary endothelial progenitor cells (EPCs). CRISPR/Cas9 gene editing was used to genetically label and purify mouse pulmonary EPCs.

[Stem Cell Research & Therapy] Scientists assembled five groups of chosen endothelial progenitor cells (EPCs)-related genes/factors using PubMed literature and Gene Ontology databases. This shortened database of EPC factors was fed into publically published transcriptome matrix to compare their expression between endothelial colony-forming cells, HUVECs, and two adult endothelial cell types from the skin and adipose tissue.