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Pulmonary Cell NewsResearchers used induced pluripotent stem cell technology and established a 3D, organoid-like differentiation system maintaining the structural cellular integrity to evaluate the effect of cytokines on embryonic hematopoietic development.
[Haematologica]
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Ackermann, M., Haake, K., Kempf, H., Kaschutnig, P., Weiss, A.-C., Nguyen, A. H. H., Abeln, M., Merkert, S., Kühnel, M. P., Hartmann, D., Jonigk, D., Thum, T., Kispert, A., Milsom, M. D., & Lachmann, N. (2021). A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification. Haematologica, 106(5), 1354–1367. https://doi.org/10.3324/haematol.2019.228064 Cite
