eosinophils

[Cancer Research] Upregulation of IL-33 instigated type-2 inflammation in the metastatic microenvironment, and mediated recruitment of eosinophils, neutrophils and inflammatory monocytes to lung metastases.

[Nature Immunology] Scientists describe an unexpected function of ST2+ regulatory T cells in suppressing the innate immune response in the lung to environmental allergens without altering the adaptive immune response.

[iScience] Researchers examined the roles of group 2 innate lymphoid cells (ILC2s) in amebic liver abscesses formation. Hepatic ILC2 numbers were significantly increased and they produced robust levels of IL-5.

[Scientific Reports] Researchers characterized the gastric mucosal inflammatory response associated with gastric MALT lymphoma (GML) and identified APRIL-producing cells in two model systems: an APRIL transgenic mouse model of GML induced by Helicobacter infection and human gastric biopsy samples from Helicobacter pylori-infected GML patients.

[Experimental Hematology] Researchers report that traditional, hematopoietic stem cell-derived myeloid cells in the adult lung, peripheral blood, and bone marrow also depend on interleukin 7 receptor expression.

[Mucosal Immunology] Investigators evaluated the effects of an anti-Siglec-8 monoclonal antibody in non-allergic disease models of experimental cigarette-smoke-induced chronic obstructive pulmonary disease and bleomycin-induced lung injury in Siglec-8 transgenic mice.