epidermal stem cells

[Advanced Science] An hiPSC-derived epithelial and mesenchymal organoid model in a 3D culture system for localized scleroderma therapy was established.

[Journal of Cell Communication and Signaling] Researchers found that matrix metalloproteinases were responsible for ultraviolet (UV)-mediated Collagen 17A degradation in both in vitro keratinocytes and in vivo mouse skin.

[Cold Spring Harbor Perspectives in Biology] Investigators review diverse cellular interactions and highlight how far-reaching signals can be transmitted at the local level to enable skin stem cells to tailor their actions to suit the particular occasion and optimize fitness.

[Burns & Trauma] The authors observed the effect of calcium silicate (CS) on human epidermal stem cells and investigated its possible mechanism. They explored the therapeutic effect of CS on wound healing and re-epithelialization.

[Stem Cell Research & Therapy] To inhibit the differentiation of epidermal stem cells (EpSCs) and maintain their stemness, scientists developed an electrospun polycaprolactone + cellulose acetate micro/nanofiber for the culture and transplantation of EpSCs.

[Cell Stem Cell] Scientists demonstrated that Lgr6 marked a regionally restricted population of epidermal stem cells that interacted with nerves and specialized in wound re-epithelialization.