epithelial cells

[Genes and Environment] Researchers quantitatively measured the methylation content of Alu and LINE1 in particulate matter-treated normal human bronchial epithelial cells and normal human epidermal keratinocytes by using whole-genome bisulfite sequencing and pyrosequencing.

[Respiratory Research] In vivo, intraperitoneal injection of Nifuroxazide relieved and reversed pulmonary fibrosis caused by bleomycin bronchial instillation.

[Journal of Immunology] The authors reported that inhalation of the TLR4 ligand LPS upregulated cell surface MHC class I by ∼25-fold on the three subtypes of mouse lung epithelial cells.

[Immunological investigations] CircRNA paralemmin 2 modulated lipopolysaccharide-caused murine lung epithelial cell injury by the microRNA-330-5p (miR-330-5p)/rho-associated coiled-coil containing protein kinase 2 (ROCK2) pathway, providing a therapeutic target for acute lung injury.

[Nature Communications] Researchers reported the mechanism altering mitochondrial function and OXPHOS in stress-induced senescent fibroblasts.

[Nature Communications] The authors suggested that KIRREL1 functioned as a feedback regulator of the mammalian Hippo pathway through sensing cell-cell interaction and recruiting SAV1 to cell-cell contact sites.