epithelial cells

[Proceedings of the National Academy of Sciences of the United States of America] Investigators comprehensively analyzed the antiviral activity of all IFNα subtypes against SARS-CoV-2 to identify the underlying immune signatures and explore their therapeutic potential.

[Nature Protocols] The authors provided a reproducible protocol to robustly induce intestinal morphogenesis in a microfluidic gut-on-a-chip as well as in a Transwell-embedded hybrid chip.

[Cell Death Discovery] Scientists demonstrated that SpvB promoted necroptosis of intestinal epithelial cells and contributed to the destruction of the intestinal barrier during Salmonella infection.

[Molecular Nutrition & Food Research] The authors investigated the effects of a cranberry proanthocyanidin-rich extract and two of its gut microbial metabolites, 3,4-dihydroxyphenylacetic acid and 3-(4-hydroxyphenyl)-propionic acid, on intestinal epithelial cells microRNA expression and their downstream pathways at homeostasis and in inflammatory conditions.

[eLife] Investigators uncovered a novel antiviral function of N6-methyladenosine (m6A) modification during rotavirus infection in small bowel intestinal epithelial cells.

[Molecular Medicine] Researchers explored if omega-3 fatty acids could affect sepsis-induced intestinal injury with the involvement of the microRNA-1-3p/Notch3-Smad axis.