epithelial cells

[Cellular Signalling] Scientists analyzed Clinical Proteomic Tumor Analysis Consortium, colon tissue microarray, and colon cancer cells to evaluate the ESRP1 expression levels in colorectal cancer subtypes.

[Journal of Radiation Research] Researchers assessed the response to radiation dose and dose-rate by measuring both organoid-forming potential and the percentage of stem cells in the crypts.

[Biochimica Et Biophysica Acta-Molecular Basis of Disease] Biliary progenitor cells were isolated and grown as organoids from gallbladders. Cells and tissue were analyzed using histology, immunohistochemistry and Western blot assays.

[Theranostics] The authors generated mutant mouse strains with heterozygous germline deletion of Gata3 in p18INK4c (p18) deficient backgrounds and developed a Gata3 depleted mammary tumor model system to determine the role of Gata3 loss in controlling cell proliferation and aberrant differentiation in mammary tumor development and progression.

[International Journal of Biological Sciences] Researchers found that decreased expression of ITGB4 was negatively correlated with the level of MUC5AC in childhood airway epithelial cells following respiratory syncytial virus (RSV) infection.

[International Journal of Biological Sciences] By applying untargeted global metabolomics approach, the authors showed that arsenic was highly capable of perturbing the intracellular metabolic programs of the human bronchial epithelial cells, some of which were prominent hallmarks of cancer cell metabolism.