[Bioengineered] The prostatic epithelial cell RWPE-1 and prostate cancer cell DU145 were exposed to Fraxetin to detect the changes in cell viability using cell counting kit-8 assay.
[Microscopy Research and Technique] Investigators used an organotypic model of wound healing and we seeded keratinocytes on a adipose-derived MSC-induced dermal matrix. Conventional hematoxylin–eosin stain and immunohistochemistry staining for Ki67, p63 and pan-keratins were performed at different timepoints.
[Toxicology Letters] Small intestinal organoids were used to assess if arsenic exposure would also impair intestinal stem cell differentiation. No changes in markers of differentiated epithelial cells were seen.
[Scientific Reports] Researchers analyzed in vitro the effect of lysophosphatidic acid (LPA)18:1 and the LPA receptor 1 (LPAR1), LPAR3, and LPAR2 inhibitor Ki16425 on cellular functions of different human breast cancer cell lines and the human breast epithelial cell line, as well as Interleukin 8, Interleukin 6 and tumor necrosis factor-alpha cytokine secretion after LPA-incubation.
[iScience] Knockdown of betacellulin inhibited the growth of EGFR-mutant human lung adenocarcinoma cells in culture and their tumor-forming ability in mice.