epithelial cells

[Scientific Reports] Scientists evaluated the toxicity of stainless and mild steel particles generated via gas–metal arc welding using primary human small airway epithelial cells and ToxTracker reporter murine stem cells, which tracked activation of six cancer-related pathways.

[Cell Reports] Mice with an intestinal epithelial cells-intrinsic deletion of MHC class II were healthy but have fewer microbial-bound IgA, regulatory T cells, and immune repertoire selection.

[Pulmonary Pharmacology & Therapeutics] Researchers investigated the effects of PCI-34051-induced human bronchial epithelial cells-derived exosomes on human bronchial smooth muscle cells and the key exosomal miRNAs involved in this process.

[Cell Cycle] Exosomes were extracted from normal human prostatic epithelial cell lines and prostate cancer (PCa) cell lines by ultrahigh speed centrifugation. Results of Western blot indicated that Alix, HSC70 and TSGl01 protein levels were upregulated in exosomes derived from PCa cells.

[Nature Communications] Investigators demonstrated the stem cell transcription factor Krüppel-like factor 5 (KLF5) was low or absent in prostate cancers prior to endocrine therapy, but induced in a subset of castration-resistant prostate cancer (CRPC), including CRPC displaying lineage plasticity.

[BMC Research Notes] Scientists evaluated whether placental extract influences epithelial–mesenchymal transition (EMT) and fibrosis through cytokine-induced EMT in the retinal pigment epithelial cells, in vitro.