Researchers report a method to generate a 3D motor neuron model with segregated and directed axonal outgrowth. iPSC-derived motor neurons were cultured in extracellular matrix gel in a microfluidic platform.
[Scientific Reports]
Spijkers, X. M., Pasteuning-Vuhman, S., Dorleijn, J. C., Vulto, P., Wevers, N. R., & Pasterkamp, R. J. (2021). A directional 3D neurite outgrowth model for studying motor axon biology and disease. Scientific Reports, 11(1), 2080. https://doi.org/10.1038/s41598-021-81335-z Cite
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