extracellular matrix

[Biology Open] Investigators review apicobasal crosstalk of two well-established models of membrane remodeling taking place during Drosophila melanogaster embryogenesis: amnioserosa cell shape oscillations during dorsal closure and subcellular tube formation in tracheal cells.

[Molecular Therapy-Oncolytics] Investigators combinated an oncolytic adenovirus carrying Decorin with a CAR-T targeting carbonic anhydrase IX to perform the anti-tumor activity for renal cancer cells.

[Disease Models & Mechanisms] Researchers elaborate on a bi-phasic effect of gelatin in skeletal muscle regeneration, mediated by hormetic effects of reactive oxygen species.

[Journal of Molecular Histology] Scientists investigated the role of Runt-related transcription factor 3 (RUNX3) in extracellular matrix remodelling and vascular smooth muscle cells function, and further explored the underlying mechanism.

[Journal of Molecular and Cellular Cardiology] Investigators demonstrated marker expression and matrix competency of cardiac fibroblasts developed through a developmentally conserved epicardial pathway as shown next to primary human cardiac fibroblasts.

[Proceedings of the National Academy of Sciences of the United States of America] For key structural factors within the nucleus and ECM, the authors discovered specific gene-gene scaling exponents across many of the 32 tumor types in The Cancer Genome Atlas, and they demonstrated utility in predicting patient survival as well as scaling-informed machine learning.