extracellular matrix

[Scientific Reports] To examine the interaction between trabecular meshwork cells on Schlemm’s canal endothelial cells, researchers investigated whether exosomes contributed to intercellular communication.

[PLoS One] Researchers studied the effect of dietary salt loading on inflammatory process and related extracellular matrix remodeling in the skin. The effect of high salt concentration on dermal fibroblasts and peripheral blood mononuclear cells was investigated in vitro.

[Microsystems & Nanoengineering] Investigators presented a simple strategy for using optical media discs with nanogrooves and other polymer-based substrates nanomolded from the discs to directly culture muscle cells to study their response to the effect of biophysical cues such as nanotopography and substrate stiffness.

[Cell] Scientists present evidence that the eDNA-based architecture of biofilm development relied on the rare Z-form, and demonstrated that the universal bacterial DNABII family of proteins stabilized both bacterial- and host-eDNA in the Z-form in situ.

[Nature Communications] Scientists found that ensheathing glia were polarized with a basolateral plasma membrane rich in phosphatidylinositol-(3,4,5)-triphosphate and the Na+/K+-ATPase Nervana2 that abuted an ECM formed at neuropil-cortex interface.

[Gastric Cancer] SHG assays with mouse xenograft models and human samples demonstrated cancer-associated fibroblasts-derived hyaluronan and proteoglycan link protein 1 (HAPLN1) increased tumour invasiveness through ECM remodeling.