fibroblasts

[Scientific Reports] Scientists worked with electrospun nanofiber scaffold named that was composed of polyvinyl alcohol/iota carrageenan and doped with partially reduced graphene oxide that was successfully synthesized for wound healing and skin repair.

[Scientific Reports] Rat primary cardiac fibroblasts were isolated and transformed into myofibroblasts using 5 ng/ml TGF-β1. Transformation of cells to myofibroblasts was confirmed with the presence of α-smooth muscle actin using Western blot.

[Molecular Cancer] Investigators shed light on recent advances regarding the direct and indirect crosstalk between cancer-associated fibroblasts (CAFs) and infiltrating immune cells and further summarize the possible immunoinhibitory mechanisms induced by CAFs in the tumor microenvironment.

[BMC Cancer] Investigators conducted microarray gene expression analysis and compared FX-9 exposed and unexposed prostate cancer cells, followed by pathway analysis and gene annotation to functional processes.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists presented a multimodal -omics platform for the comprehensive study of cell populations in complex tissue, which allowed them to characterize the cells involved in wound healing across both time and space.

[Cell] Investigators deconvoluted the human pancreatic tumor microenvironment through large-scale integration of histology-guided regional multiOMICs with clinical data and patient-derived preclinical models.