Researchers investigated the initiation of fibronectin (FN) matrix assembly using fibroblasts that assemble parallel extracellular matrix fibrils and found that matrix assembly sites, where FN fibrillogenesis is initiated, were oriented in parallel at the cell poles.
[Molecular Biology of the Cell]
Garrison, C. M., & Schwarzbauer, J. E. (2021). Fibronectin fibril alignment is established upon initiation of extracellular matrix assembly. Molecular Biology of the Cell, mbc.E20-08-0533. https://doi.org/10.1091/mbc.E20-08-0533 Cite
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