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flow cytometry

Combination Treatment of Docetaxel with Caffeic Acid Phenethyl Ester Suppresses the Survival and the Proliferation of Docetaxel-Resistant Prostate Cancer Cells via Induction of Apoptosis...

[Journal of Biomedical Science] Combination treatment of docetaxel with caffeic acid phenethyl ester effectively suppressed the proliferation and survival of docetaxel-resistant prostate cancer cells via inhibition of Bcl-2 and c-Myc as well as induction of metabolism interference.

Phytochemical Analysis of Daphne pontica L. Stems with Their Pro-Apoptotic Properties against DU-145 and LNCaP Prostate Cancer Cells

[Daru-Journal of Pharmaceutical Sciences] Scientists analyzed the phytochemistry and screen the cytotoxic activity of new bioactive compounds against a panel of cancer cells, in addition to proapototic properties against prostate cancer cells.

ATR Inhibitor AZD6738 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting Repair of DNA Damage

[Oncology Reports] In vitro, the AZD6738/5‑FU combination increased the number of mitotic cells according to flow cytometry, decreased the checkpoint kinase 1 phosphorylation levels and increased cleaved caspase‑3 and phosphorylated form of H2A.X variant histone levels according to western blotting, and decreased the proliferation rate of four colon cancer cell lines according to cell viability experiments.

lncRNA TUG1 Protects Intestinal Epithelial Cells from Damage Induced by High Glucose and High Fat via AMPK/SIRT1

[Molecular Medicine Reports] Protein expression was detected by western blotting. Cell Counting Kit‑8 assays were performed to analyze cell viability, and flow cytometry and a TUNEL assay was performed to evaluate cell apoptosis.

Circular RNA-UBE2D2 Accelerates the Proliferation and Metastasis of Non-small Cell Lung Cancer Cells via Modulating microRNA-376a-3p/Eukaryotic Translation Initiation Factor 4γ2 Axis

[Bioengineered] Scientists suggested that circ-UBE2D2 promoted the proliferation, migration and invasion but restrained apoptosis of lung cancer cells by regulating miR-376a-3p/eukaryotic translation initiation factor 4γ2 axis.

Local Inhibition of TGF-β1 Signaling Improves Th17/Treg Balance but Not Joint Pathology during Experimental Arthritis

[Scientific Reports] Murine splenocytes were differentiated into T helper 17 cells, and the effect of the TGF-βRI inhibitor SB-505124 was studied.

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