Tag results:

flow cytometry

Knockdown of circRNA Paralemmin 2 Ameliorates Lipopolysaccharide-Induced Murine Lung Epithelial Cell Injury by Sponging miR-330-5p to Reduce ROCK2 Expression

[Immunological investigations] CircRNA paralemmin 2 modulated lipopolysaccharide-caused murine lung epithelial cell injury by the microRNA-330-5p (miR-330-5p)/rho-associated coiled-coil containing protein kinase 2 (ROCK2) pathway, providing a therapeutic target for acute lung injury.

Identification of UAP1L1 as a Critical Factor for Prostate Cancer and Underlying Molecular Mechanism in Tumorigenicity

[Journal of Translational Medicine] The effects of UAP1-like-1 (UAP1L1) on prostate cancer were investigated by detecting the proliferation, migration, invasion and apoptosis of prostate cancer cells in vitro using MTT, wound healing, Transwell and flow cytometry assay, and the tumor growth in vivo.

PD-L1 Blockade Liberates Intrinsic Antitumourigenic Properties of Glycolytic Macrophages in Hepatocellular Carcinoma

[Gut] Scientists elucidated the nature, regulation and functional relevance of PD-L1+ host cells in HCC.

Dual-sgRNA CRISPR/Cas9 Knockout of PD-L1 in Human U87 Glioblastoma Tumor Cells Inhibits Proliferation, Invasion, and Tumor-Associated Macrophage Polarization

[Scientific Reports] Utilizing dual-single guide RNAs (sgRNAs) and a homology-directed repair template with the CRISPR/Cas9 gene-editing system is a promising avenue for the treatment of glioblastoma multiforme.

Human Umbilical Cord Mesenchymal Stem Cells Alleviate the Imbalance of CD4+ T Cells via Protein Tyrosine Phosphatase Non-Receptor Type 2/Signal Transducer and Activator of...

[Endocrine Journal] Researchers investigated the therapeutic effect of human umbilical cord MSCs on experimental autoimmune thyroiditis (EAT) and the underlying mechanisms by utilizing a porcine thyroglobulin-induced EAT rat model.

Silencing of LINC01963 Enhances the Chemosensitivity of Prostate Cancer Cells to Docetaxel by Targeting the miR-216b-5p/TrkB Axis

[Laboratory Investigation] Silencing LINC01963 inhibited TrkB protein level to enhance the chemosensitivity of PC3-DR to docetaxel by means of competitively binding to miR-216b-5p.

Popular