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flow cytometry

Growth and Mineralization of Osteoblasts from Mesenchymal Stem Cells on Microporous Membranes: Epithelial-Like Growth with Transmembrane Resistance and pH Gradient

[Biochemical and Biophysical Research Communications] MSCs were characterized by flow cytometry with more than 90% CD44 and 75% Sca-1 labeling. Mineralization was validated with paracellular alkaline phosphatase activity, collagen birefringence, and mineral deposition confirming MSCs identity.

The Proliferation and Migration of Atherosclerosis-Related HVSMCs Were Inhibited by Downregulation of lncRNA XIST via Regulation of the miR-761/BMP9 Axis

[Kaohsiung Journal of Medical Sciences] Scientists found that lncRNA XIST was related to the abnormal proliferation and migration of human vascular smooth muscle cells (HVSMCs), and thus, the mechanism by which XIST regulated HVSMCs was further investigated.

Circ-LAMP2 Regulates Aortic Smooth Muscle Cell Proliferation and Apoptosis in Thoracic Aortic Aneurysm via Modulation of Autophagy and NF-κB Pathway

[Human Pathology] The apoptosis of smooth muscle cells is a major feature of thoracic aortic aneurysm. Scientists investigated the roles of circ_0091434 in human aortic smooth muscle cells.

Involvement of Multiple Scavenger Receptors in Advanced Glycation End Product-Induced Vessel Tube Formation in Endothelial Cells

[Experimental Cell Research] Researchers examined the involvement of advanced glycation end (AGE)-related receptors on AGE-induced angiogenesis in endothelial cells.

Atovaquone-HSA Nano-Drugs Enhance the Efficacy of PD-1 Blockade Immunotherapy by Alleviating Hypoxic Tumor Microenvironment

[Journal of Nanobiotechnology] The authors exploited atovaquone/albumin nanoparticles to improve bioavailability and tumor targeting of atovaquone, enhancing the efficacy of anti-PD-1 therapy by normalizing tumor hypoxia.

Curcumol Inhibits the Malignant Progression of Prostate Cancer and Regulates the PDK1/AKT/mTOR Pathway by Targeting miR-9

[Oncology Reports] Researchers analyzed the effect of curcumol on prostate cancer and identify its possible internal regulatory pathway using in vitro cell culture and in vivo tumor model experiments.

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