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flow cytometry

Hepatoprotective Effects of Sevoflurane against Hepatic Ischemia-Reperfusion Injury by Regulating microRNA-124-3p-Mediated TRAF3/CREB Axis

[Cell Death Discovery] Scientists defined the role of sevoflurane in hepatic ischemia-reperfusion injury as well as its underlying mechanism.

An Organoid Model of Colorectal Circulating Tumor Cells with Stem Cell Features, Hybrid EMT State and Distinctive Therapy Response Profile

[Journal of Experimental & Clinical Cancer Research] Investigators generated organoids from circulating tumor cells isolated from an orthotopic colorectal cancer xenograft model.

Human Pulmonary Artery Smooth Muscle Cell Dysfunction Is Regulated by miR-509-5p in Hypoxic Environment

[Cell Cycle] The role of miR-509-5p in hypoxia-induced pulmonary arterial smooth muscle cells (PASMCs) and the underlying mechanism were explored. PASMCs were cultured under both normoxia and hypoxia conditions.

Curcumin Alleviates Lipopolysaccharides-Induced Inflammation and Apoptosis in Vascular Smooth Muscle Cells via Inhibition of the NF-κB and JNK Signaling Pathways

[inflammopharmacology] Researchers investigated the effect of curcumin on vascular smooth muscle cells inflammation induced by lipopolysaccharide and its mechanism.

Forensic and Clinical Applications of Biomarkers of Cardiovascular Disease

[Disease Markers] Ferroptosis may be involved in the occurrence and development of Ischemic heart disease (IHD). Primary cardiomyocytes were treated with H2O2 to simulate the IHD in vitro model.

Proteomic Analysis Distinguishes Extracellular Vesicles Produced by Cancerous versus Healthy Pancreatic Organoids

[Scientific Reports] Researchers utilized high resolution flow cytometry to detect EVs in the plasma of patients with pancreatic ductal adenocarcinoma (PDAC) and in the supernatants of PDAC and healthy control pancreatic organoid cultures.

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