glioma stem cells

[Experimental Cell Research] Researchers explored the efficacy of the domains of secreted frizzled-related protein 4 (sFRP4) in inhibiting the key hallmarks of glioblastoma such as invasion, metastasis, and stemness.

[Molecular Cancer Research] Researchers characterized the time-dependent impact of regadenoson on brain endothelial cell interactions and paracellular transport, using mouse and rat brain endothelial cells and tumor models.

[Cell Reports] Scientists showed that patient-derived glioma stem cells recruited elevated levels of proteins that ensured the temporal cilium disassembly, leading to suppressed ciliogenesis.

[Cell Reports] Investigators showed that patient-derived glioma-stem cells recruited elevated levels of proteins that ensure the temporal cilium disassembly, leading to suppressed ciliogenesis.

[Neurochemistry International] The influence of nitric oxide and nitric oxide synthase (NOS) activity on glioma stem cells seem to be of particular importance. The use of specific inhibitors may allow the reduction of tumor growth and its tendency to relapse.

[Biochimica et Biophysica Acta-Reviews On Cancer] Scientists summarize different strategies that intensify the temozolomide effect such as MGMT inhibition, development of novel imidazotetrazine analog, and combination therapy; with an aim to incorporate a successful treatment and increased overall survival in glioblastoma patients.