Netrin-Like Domain of sFRP4, a Wnt Antagonist Inhibits Stemness, Metastatic and Invasive Properties by Specifically Blocking MMP-2 in Cancer Stem Cells from Human Glioma Cell Line U87MG

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Researchers explored the efficacy of the domains of secreted frizzled-related protein 4 (sFRP4) in inhibiting the key hallmarks of glioblastoma such as invasion, metastasis, and stemness.
[Experimental Cell Research]
Abstract